The use of bioprinting technology for the development of 3D tissue-mimicking structures is a key tool to answer basic and applied research questions in areas such as tissue engineering and the search for pharmaceutical molecules. Additionally, other in vitro platforms such as cell lines derived from different tissues and 2D cell cultures are also suitable systems for various purposes ranging from disease models to the evaluation of therapeutic drug targets. Furthermore, the identification and isolation of therapeutic molecules are crucial to respond to emerging diseases and even health emergencies. This is why in this line of research and in collaboration with Professor Juan Carlos Cruz we cover different and innovative biomedical applications, which are based on the study and implementation of cellular systems such as:

  1. 3D bioprinting of tissue models using bioinks formulated from synthetic and natural materials, such as those derived from decellularized extracellular matrices.

  2. 2D and 3D cell culture systems as in vitro platforms for the search and selection of therapeutic molecules.

  3. Selection of pharmacological compounds from natural sources and traditional uses of Colombian flora and fauna.

  4. Study of mechanical and chemical signals to control the differentiation and fate of human mesenchymal stem cells.

  5. Biocompatibility tests of polymers and nanomaterials for different biomedical applications in regenerative medicine according to ISO 10993.

Proyectos en Bioimpresión

El enfoque principal de esta línea de investigación es la de diseñar hidrogeles de matriz extracelular (ECM) a base de submucosa intestinal (SIS) y placenta porcina (PAM). En este diseño trabajamos principalmente en las características físico-químicas de estos hidrogeles/biotintas como insumo básico de la tecnología de bioimpresión 3D por extrusión (BIOX-Cellink). En particular estamos interesados en la imprimibilidad, fidelidad y biocompatibilidad de dichas biotintas. De acuerdo con esto, durante los últimos 3 años hemos desarrollado hidrogeles biocompatibles con las propiedades del ambiente extracelular (ECM), las propiedades reológicas indicadas para su extrusión a través del sistema de bioimpresión. Esto con el propósito de garantizar que las propiedades mecánicas ajustables por medio de moléculas fotoestimulables que facilitan el entrecruzamiento de las cadenas poliméricas presentes.

Actualmente en nuestro grupo tenemos como objetivo utilizar nuestras biotintas para desarrollar un modelo 3D de piel bioimpreso; así como un modelo de epitelio pigmentario en colaboración con el Hospital Militar Central.


Patentes 

U.S patent application - EXTRUDABLE PHOTOCROSSLINKABLE HYDROGEL AND METHOD FOR ITS PREPARATION. 16/992,708 (Nuestra Ref.: USP2020/000027) (Sometida el 14 de agosto-2020)


Financiación 

2020

Proyecto en conjunto con el Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud - IDCBIS. Desarrollar un sistema in vitro de expansión y diferenciación de CMH utilizando hidrogeles derivados de matriz extracelular y a través de la técnica de manufactura basada en bioimpresión 3D por extrusión.

Convocatoria conjunta Hospital Militar-Uniandes.Desarrollo de un Modelo Bioimpreso de Epitelio Pigmentario de la Retina Humana.

DAAD: Convocatoria RISE Worldwide.Development of a hydrogel from decellularized porcine placenta for bioink applications. Financiación de practicantes alemanes en Colombia-2021.


2018

Fondo de Apoyo a Profesores Asistentes. FAPA.Diseño y evaluación de biotintas a base de hidrogeles de submucosa intestinal y placenta porcina para la fabricación de equivalentes de piel humana por bioimpresión.


Publicaciones 

Peer reviewed Journal articles

2021

Céspedes-Valenzuela DN, Sánchez-Rentería S, Cifuentes J, Gantiva-Diaz M, Serna JA, Reyes LH, Ostos C, Cifuentes-De la Portilla C, Muñoz-Camargo C, Cruz JC. Preparation and Characterization of an Injectable and Photo-Responsive Chitosan Methacrylate/Graphene Oxide Hydrogel: Potential Applications in Bone Tissue Adhesion and Repair. Polymers (Basel). 2021 Dec 30;14(1):126. do: 10.3390/polym14010126. PMID: 35012148; PMCID: PMC8747203.

Serna, J.A.; Rueda-Gensini, L.; Céspedes-Valenzuela, D.N.; Cifuentes, J.; Cruz, J.C.; Muñoz-Camargo, C. Recent Advances on Stimuli-Responsive Hydrogels Based on Tissue-Derived ECMs and Their Components: Towards Improving Functionality for Tissue Engineering and Controlled Drug Delivery. Polymers 2021, 13, 3263. https://doi.org/10.3390/polym13193263

Laura Rueda-Gensini, Julian A. Serna, Javier Cifuentes, Juan C. Cruz, Carolina Muñoz-Camargo. 2021. Graphene oxide-embedded ECM-derived hydrogel as a multiresponsive platform for 3D bioprinting applications. International Journal of Bioprinting 2021; 7(3): 353. doi: 10.18063/ijb.v7i3.353


2019

Serna J. A., Talero V.A., Flórez S.L, Briceño J.C, Muñoz-Camargo C., Cruz J. C. 2019. Formulation and Characterization of a SIS based photocrosslinkable bioink. Polymers. Mar 26;11(3). pii: E569. doi: 10.3390/polym11030569.


Artículos en Congresos 

2021

CIIBBI 2021.Julian A Serna, Javier Cifuentes, Laura Rueda, Luis A Ruiz, Bernardo Quijano, Paula X Pavía, Camila A Camargo, Juan C Cruz ,Carolina Muñoz-Camargo. Amniotic membrane-derived extracellular matrix-based hydrogels for the improved maturation of human retinal pigment epithelium in vitro models.

CIIBBI 2021.Laura Liliana Delgado-Murillo, Bellaneth Devia, Ana María Perdomo-Arciniegas, Juan Carlos Cruz, Carolina Muñoz-Camargo. Standardization of a 3D bioprinting platform for hematopoietic progenitor cells proliferation: conditions for a small intestinal submucosa based bioink.

CIIBBI 2021.Daniela N. Céspedes-Valenzuela, Santiago Sánchez-Rentería, Carolina Muñoz-Camargo, Juan C. Cruz. Chitosan methacrylate-based bioadhesive: towards a photoresponsive and extrudable material for bone fracture repair.

CIIBBI 2021.Cristian Felipe Rodríguez Ospino, Laura Ortiz Calderon, Kevin Alejandro Giraldo Rodríguez, Carolina Muñoz Camargo, Juan Carlos Cruz Jimenez. In silico study of spheroids fusion through magnetic field gradients.

ACS Fall. 22-26 agosto 2021.Daniela Céspedes-Valenzuela, Santiago Sánchez-Renteria,Javier Cifuentes, Carolina Muñoz-Camargo, Juan C. Cruz. Development of a photo-crosslinkable bioadhesive based on methacryloyl-modified chitosan and functionalized reduced graphene oxide for the treatment of bone fractures.

ACS Fall. 22-26 agosto 2021.Daniela Céspedes-Valenzuela, Santiago Sánchez-Renteria, Laura Rueda-Gensini, Julián Andrés Serna, Carolina Muñoz-Camargo, Juan C. Cruz. Novel photo- and thermo- responsive composite hydrogels based on functionalized rGO and modified SIS/chitosan polymers for localized treatment of malignant cutaneous melanoma.

ACS Fall. 22-26 agosto 2021.Laura Delgado-Murillo, Isabella Muñoz, Ana María Perdomo-Arciniegas, Juan C. Cruz, Carolina Muñoz-Camargo. Decellularized porcine placenta bioink as a microenvironment for increasing hematopoietic cells proliferation in transplants.

ACS Fall. 22-26 agosto 2021.Maria A. Rodriguez-Soto, Natalia A. Suarez V.,Alejandra Riveros, Andres J. Garcia-Brand,Mónica Cuellar, Carolina Muñoz-Camargo, Juan C. Cruz, Nestor Sandoval, Juan C. Briceño. Scaffolds with hierarchical bioactive properties through multilayered 3D configurations via tunable biodegradable PCL.


2019

Termis Annual Conference 2019.Alejandra Suarez-Arnedo, Sebastian Londoño, Julian A. Serna, Javier Cifuentes, Laura Muñoz, Juan C. Cruz, Carolina Muñoz-Camargo. 3D Bioprinted Dermoepidermal Human Skin Equivalent as an Experimental in vitro Model for the Evaluation of Antibacterial Topical Treatments.

Termis Annual Conference 2019.Laura Rueda, Julian A. Serna, Javier Cifuentes, Alejandra Suarez-Arnedo, Juan C. Cruz, Carolina Muñoz-Camargo. Thermo-, Photo- and Electro-Sensitive ECM-Based Bioinks for 3D Bioprinting Applications.

8th International Conference on Bioengineering and Nanotechnology.Julián A. Serna, Javier Cifuentes, Juan C. Cruz, Carolina Muñoz-Camargo. Formulation, characterization and evaluation of a photocrosslinkable bioink for skin bioprinting based on decellularized SIS.

8th International Conference on Bioengineering and Nanotechnology.Paula Guerrero, Alejandra-Suarez Arnedo, Juan Carlos Cruz, Carolina Muñoz-Camargo. Decellularization of fetal porcine epidermal and amniotic membranes for the development of regenerative bioinks.


Posters en congresos 

2018

Biomedical Engineering Society (BMES) Annual Meeting, October 17-20, 2018 in Atlanta.Serna J., Talero V., Florez S., Cruz J.C., Briceño J.C., Muñoz-Camargo C. High-Performance Bioprinting Strategies of Tunable and Photocrosslinkable SIS-dECM Bioinks by in silico and Experimental Evaluation of Key Extrusion Parameters.


Divulgación Científica 

2019

Muñoz-Camargo C, Cruz J C., Serna J. (2019) Bioimpresión 3D. Anales De Ingeniería (ISSN 0120-0429) Colombia.

 

Bothrops

Figura 1. Proceso de bioimpresion utilizando biotinta de SIS placeenta porcina y viabilidad celular post-impresión. Tomado de: Formulation and Characterization of a SIS Based Photocrosslinkable Bioink. Serna et al. Polymers 11(3), 569:2019

 

Investigadores 

Carolina Muñoz Camargo

Líder y Profesora Asociada


Juan C. Cruz

Co-Director y Profesor Asociado



Co-investigadores externos 

Luis Alberto Ruiz

Médico Oftalmólogo del Hospital Militar Central


Bernardo Quijano

Médico Oftalmólogo del Hospital Militar Central


Paula Pavia

Coordinadora Investigación Básica Hospital Militar Central


Ana María Perdomo

IDCBIS


Bellaneth Devia

Estudiante PhD, Universidad Nacional-IDCBIS



Profesor afiliado 

Juan Carlos Briceño

Profesor Titular



Investigadores Senior 

Javier Cifuentes

Investigador MSc



Estudiantes de Posgrado 

María Alejandra Castilla

Estudiante PhD


Laura Delgado

Estudiante MSc


Laura Rueda

Estudiante MSc


Cristián Rodriguez

Estudiante MSc


Simón Jaramillo

Estudiante MSc



Estudiantes graduados 

Alejandra Suarez Arnedo

Estudiante de Maestría (egresada)


Paula Andrea Guerrero

Estudiante de Maestría (egresada)



Estudiantes de Intercambio 

Nikolina Lipovcic

Undergraduate Student

München - Technische Universität München (Germany)


Sophia Conney

Online internship: Comsol and specifically the simulations of Graphene-Polymer systems.

Purdue-Uniandes SURGE program.



 

carolina muñoz

Carolina Muñoz, PhD

Group Director - Associate Professor

 

juan carlos cruz

Juan Carlos Cruz, PhD

Co-Director - Associate Professor

javier cifuentes

Javier Cifuentes, MSc.

Researcher

andrés julián garcía

Andrés Julián García

Researcher

daniela rubio

Daniela Rubio, MSc.

Researcher

laura rueda

Laura Rueda

Researcher

alejandra castilla

María Alejandra Castilla, PhD

PhD Student in Engineering

simon jaramillo

Simón Jaramillo, MSc.

Master's Student in Biomedical Engineering

valentina jaramillo

Valentina Jaramillo, MSc.

Master's Student in Biomedical Engineering

cristian rodríguez

Cristian Rodríguez, MSc.

Master's Student in Biomedical Engineering

juanita monje

Juanita Monje Dussan

Master's Student in Biomedical Engineering

mónica gantiva

Mónica Gantiva

Master's Student in Biomedical Engineering

erika díaz

Erika Díaz

Master's Student in Biomedical Engineering

juan buitrago

Juan Sebastián Buítrago

Master's Student in Computational Biology

2022

publicacion
Cifuentes, J.; Muñoz-Camargo, C.; Cruz, J.C. Reduced Graphene Oxide-Extracellular Matrix Scaffolds as a Multifunctional and Highly Biocompatible Nanocomposite for Wound Healing: Insights into Characterization and Electroconductive Potential. Nanomaterials 2022, 12, 2857. https://doi.org/10.3390/nano12162857

publicacion
Ruiz Puentes, P.; Henao, M.C.; Cifuentes, J.; Muñoz-Camargo, C.; Reyes, L.H.; Cruz, J.C.; Arbeláez, P. Rational Discovery of Antimicrobial Peptides by Means of Artificial Intelligence. Membranes 2022, 12, 708. https://doi.org/10.3390/membranes12070708

publicacion
Rodriguez-Soto, M.A.; Garcia-Brand, A.J.; Riveros, A.; Suarez, N.A.; Serrano, F.; Osma, J.F.; Muñoz Camargo, C.; Cruz, J.C.; Sandoval, N.; Briceño, J.C. Blood-Vessel-Inspired Hierarchical Trilayer Scaffolds: PCL/Gelatin-Driven Protein Adsorption and Cellular Interaction. Polymers 2022, 14, 2135. https://doi.org/10.3390/polym14112135

publicacion
Rodriguez-Soto, M.A.; Riveros, A.; Suarez Vargas, N.; Garcia-Brand, A.J.; Camargo, C.M.; Cruz, J.C.; Sandoval, N.; Briceño, J.C. Failure Analysis of TEVG’s II: Late Failure and Entering the Regeneration Pathway. Cells 2022, 11, 939. https://doi.org/10.3390/cells11060939

publicacion
Paola Ruiz Puentes, Laura Rueda-Gensini, Natalia Valderrama et al. Modeling Protein-Ligand Interactions with Graph Convolutional Networks for Interpretable Pharmaceutical Discovery, 02 February 2022, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-1262123/v1]

publicacion
Céspedes-Valenzuela DN, Sánchez-Rentería S, Cifuentes J, Gómez SC, Serna JA, Rueda-Gensini L, Ostos C, Muñoz-Camargo C, Cruz JC. Novel Photo- and Thermo-Responsive Nanocomposite Hydrogels Based on Functionalized rGO and Modified SIS/Chitosan Polymers for Localized Treatment of Malignant Cutaneous Melanoma. Front Bioeng Biotechnol. 2022 Jul 6;10:947616. doi: 10.3389/fbioe.2022.947616. PMID: 35875496; PMCID: PMC9300866.

publicacion
Riveros, A.; Garcia-Brand, A.J.; Rodriguez-Soto, M.A.; Sandoval, N.; Muñoz-Camargo, C.; Cruz, J.C.; Briceño, J.C. Computational Characterization of Mechanical, Hemodynamic, and Surface Interaction Conditions: Role of Protein Adsorption on the Regenerative Response of TEVGs. Int. J. Mol. Sci. 2022, 23, 1130. https://doi.org/10.3390/ijms23031130

publicacion
Torres, C.E.; Cifuentes, J.; Gómez, S.C.; Quezada, V.; Giraldo, K.A.; Puentes, P.R.; Rueda-Gensini, L.; Serna, J.A.; Muñoz-Camargo, C.; Reyes, L.H.; Osma, J.F.; Cruz, J.C. Microfluidic Synthesis and Purification of Magnetoliposomes for Potential Applications in the Gastrointestinal Delivery of Difficult-to-Transport Drugs. Pharmaceutics 2022, 14, 315. https://doi.org/10.3390/pharmaceutics14020315

publicacion
Laura Rueda-Gensini, Julian A Serna, Natalia I Bolaños, Jader Rodriguez, Juan C Cruz, Carolina Muñoz-Camargo. Evaluating the impact of thermal processing on the anti-inflammatory activity of non-centrifugal cane sugar: implications on cytokine secretion and TLR4 signaling. Front. Pharmacol. 2022, 13:905347. https://doi.org/10.3389/fphar.2022.905347

publicacion
Ruiz Puentes, P., Rueda-Gensini, L., Valderrama, N. et al. Predicting target–ligand interactions with graph convolutional networks for interpretable pharmaceutical discovery. Sci Rep 12, 8434 (2022). https://doi.org/10.1038/s41598-022-12180-x

 

2021

 

publicacion
Céspedes-Valenzuela DN, Sánchez-Rentería S, Cifuentes J, Gantiva-Diaz M, Serna JA, Reyes LH, Ostos C, Cifuentes-De la Portilla C, Muñoz-Camargo C, Cruz JC. Preparation and Characterization of an Injectable and Photo-Responsive Chitosan Methacrylate/Graphene Oxide Hydrogel: Potential Applications in Bone Tissue Adhesion and Repair. Polymers (Basel). 2021 Dec 30;14(1):126. do: 10.3390/polym14010126. PMID: 35012148; PMCID: PMC8747203.

publicacion
Serna, J.A.; Rueda-Gensini, L.; Céspedes-Valenzuela, D.N.; Cifuentes, J.; Cruz, J.C.; Muñoz-Camargo, C. Recent Advances on Stimuli-Responsive Hydrogels Based on Tissue-Derived ECMs and Their Components: Towards Improving Functionality for Tissue Engineering and Controlled Drug Delivery. Polymers 2021, 13, 3263. https://doi.org/10.3390/polym13193263

publicacion
Rodriguez-Soto MA, Suarez Vargas N, Riveros A, Camargo CM, Cruz JC, Sandoval N, Briceño JC. Failure Analysis of TEVG's I: Overcoming the Initial Stages of Blood Material Interaction and Stabilization of the Immune Response. Cells. 2021 Nov 12;10(11):3140. doi: 10.3390/cells10113140.

publicacion
David Arango, Amaury Bittar, Camila Ocasión. Natalia Esmeral, Carolina Muñoz-Camargo, Juan C Cruz, Luis H Reyes, Nastasha Bloch. 2020 Understanding the potential of genome editing in Parkinson's disease. Int. J. Mol. Sci. 2021, 22(17), 9241; https://doi.org/10.3390/ijms22179241

publicacion
Andres J. Garcia-Brand *, María A. Morales, Ana Sofia Hozman, Andres C. Ramirez, Luis J. Cruz, Alejandro Marañon, Carolina Muñoz-Camargo, Juan C. Cruz, Alicia Porras. Bioactive Poly(Lactic Acid) - Cocoa Bean Shell Composites for Potential Biomedical Applications: Preparation and Preliminary in vitro Characterization. Polymers 2021, 13(21), 3707; https://doi.org/10.3390/polym13213707

publicacion
Gómez SC, Quezada V, Quiroz I, Muñoz-Camargo C, Osma JF, Reyes LH, Cruz JC. Design and Manufacture of a Low-Cost Microfluidic System for the Synthesis of Giant Liposomes for the Encapsulation of Yeast Homologues: Applications in the Screening of Membrane-Active Peptide Libraries. Micromachines (Basel). 2021 Nov 10;12(11):1377. doi: 10.3390/mi12111377

publicacion
Javier Cifuentes, Vivian A. Salazar, Maria Claudia Castellanos, Mónica Cuellar, Jader Rodríguez, Juan C. Cruz, Carolina Muñoz-Camargo. Antioxidant and neuroprotective properties of non-centrifugal cane sugar and other sugarcane derivatives in an in vitro induced Parkinson's model. Antioxidants 2021, 10(7), 1040; https://doi.org/10.3390/antiox10071040

publicacion
Paola Ruiz Puentes, Natalia Valderrama, Cristina Gonzalez, Laura Daza,Carolina Muñoz-Camargo, Juan C. Cruz, Pablo Arbelaez. 2021.PharmaNet: Pharmaceutical discovery with deep recurrent neural networks PLOS One 16(4): e0241728. https://doi.org/10.1371/journal.pone.0241728

publicacion
Laura Rueda-Gensini, Julian A. Serna, Javier Cifuentes, Juan C. Cruz, Carolina Muñoz-Camargo. 2021. Graphene oxide-embedded ECM-derived hydrogel as a multiresponsive platform for 3D bioprinting applications. International Journal of Bioprinting 2021; 7(3): 353. doi: 10.18063/ijb.v7i3.353

 

2020

 

publicacion
Laura Rueda, Javier Cifuentes, M. Claudia Castellanos, Paola Ruiz, Julian Serna, Carolina Muñoz-Camargo, Juan C Cruz. 2020. Tailoring iron oxide nanoparticles for efficient cellular internalization and endosomal escape.Nanomaterials 2020, 10, 1816. doi.org/10.3390/pr809119810091816

publicacion
Riveros, A.; Cuellar, M.; Sánchez, P.F.; Muñoz-Camargo, C.; Cruz, J.C.; Sandoval, N.; Lopez Mejia, O.D.; Briceño, J.C. Design and Characterization of a Fluidic Device for the Evaluation of SIS-Based Vascular Grafts. Processes 2020, 8, 1198.doi.org/10.3390/pr8091198

publicacion
Alejandra Suarez-Arnedo, Felipe Torres Figueroa, Camila Clavijo, Juan C. Cruz, Carolina Muñoz-Camargo. An image J plugin for the high throughput image analysis of in vitro scratch wound healing assays. PLoS ONE 15(7): https://doi.org/10.1371/journal.pone.023256

publicacion
Riveros, A.; Cuellar, M.; Sánchez, P.F.; Muñoz-Camargo, C.; Cruz, J.C.; Sandoval, N.; Lopez Mejia, O.D.; Briceño, J.C. Design and Characterization of a Fluidic Device for the Evaluation of SIS-Based Vascular Grafts. Processes 2020, 8, 1198. https://doi.org/10.3390/pr8091198

publicacion
Paola Ruiz Puentes, María C. HenaO, Carlos E. Torres, Saúl C. Gómez, Laura A Gómez, Juan C Burgos, Pablo Arbeláez, Johann F Osma, Carolina Muñoz-Camargo, Luis H. Reyes, Juan C. Cruz. Design, screening, and testing of non-rational peptide libraries with antimicrobial activity: in silico and experimental approaches. Antibiotics 2020, 9(12), 854; https://doi.org/10.3390/antibiotics9120854

publicacion
Andrés Aranguren, Carlos E. Torres, Carolina Muñoz-Camargo, Johann F. Osma, Juan C. Cruz. 2020. Synthesis of nanoscale liposomes via low-cost microfluidic systems. Micromachines 2020, 11(12), 1050; https://doi.org/10.3390/mi11121050

publicacion
Alejandra Suarez-Arnedo, Felipe Torres Figueroa, Camila Clavijo, Juan C. Cruz, Carolina Muñoz-Camargo. An image J plugin for the high throughput image analysis of in vitro scratch wound healing assays. PLoS ONE 15(7): e0232565. doi.org/10.1371/journal.pone.0232565

publicacion
Rangel Muñoz, Nathaly; Suarez, Alejandra; Anguita, Raúl; Osma, Johann F.; Muñoz-Camargo, Carolina; Prats, Guillem;. Cruz Jiménez, Juan Carlos,Boix B, Ester; Salazar Montoya, Vivian A. Antibacterial activity of magnetite nanoparticles functionalized with RNases proteins toward intracellular infection of Pseudomonas aeruginosa. Pharmaceutics 2020, 12(7), 631; doi.org/10.3390/pharmaceutics12070631

publicacion
Spinelli R, Barrero Guevara LA, López JA, Muñoz-Camargo C, Groot de Restrepo H, Siano AS. 2020. Cytotoxic and antiproliferative activities of amphibian (anuran) skin extracts on human acute monocytic leukemia cells. Toxicon. 177: 25-34 doi: 10.1016/j.toxicon.2020.01.008.

 

2019

 

publicacion
Muñoz-Camargo C, Cruz J C., Serna J. (2019) Bioimpresión 3D. Anales De Ingeniería (ISSN 0120-0429) Colombia.

publicacion
Suarez-Arnedo, A., Narváez, D.M. , Sarmiento, P., Bocanegra, L., Salcedo, F., Muñoz-Camargo, C., Groot, H., Cruz, J.C. 2019. Tridimensional alginate disks of tunable topologies for mammalian cell encapsulation. Anal Biochem. Jun 1;574:31-33. doi: 10.1016/j.ab.2019.03.008

 

2018

 

publicacion
Muñoz-Camargo C., Salazar V.A. Barrero-Guevara L., Camargo S., Mosquera A., Groot H., and Boix E. 2018. Unveiling the Multifaceted Mechanisms of Antibacterial Activity of Buforin II and Frenatin 2.3S Peptides from Skin Micro-Organs of the Orinoco Lime Treefrog (Sphaenorhynchus lacteus) Int J Mol Sci. 19(8): 2170. doi: 10.3390/ijms19082170.

 

2020

financing
DEVELOPMENT OF A BIOPRINTED MODEL OF HUMAN RETINAL PIGMENT EPITHELIUM. Joint Call for Projects by Military Hospital-Uniandes. 2020

financing
Phase II development of agro-industrial processes to obtain higher-value products derived from sugarcane for panela production.

PI: Carolina Muñoz-Camargo, Co-investigators: Juan Carlos Cruz, Jader Rodriguez Agrosavia.

 

2019

financing
Pilot study for developing panela with added value: Functional potential with nutraceutical purposes in vitro. 828-2019 Innovation between Universities and Companies-Department Cundinamarca-Second Call.

PI: Jader Rodriguez, Carolina Muñoz, and Juan Carlos Cruz.

 

2018

financing
Pilot study for developing panela with added value: Functional potential with antioxidant and immunomodulatory activity in vitro. Colciencias Call: "Strengthening programs and research projects in medical and health sciences, with young talent and regional impact.

PIs: Carolina Muñoz-Camargo, Juan Carlos Cruz, and Jader Rodriguez.

 

financing
Design and evaluation of bio-inks based on intestinal submucosa and porcine placenta hydrogels for the manufacture of human skin equivalents by bioprinting.

PI: Carolina Muñoz C. Assistant Professor Support Fund.

 

financing
Development of agro-industrial processes to obtain higher-value products derived from sugarcane for panela production. Umbrella Project Agrosavia-Uniandes.

PI Agrosavia: Jader Rodriguez.

PI Uniandes: Carolina Muñoz. Agreement # AV17-06TV18-04

 

2017

financing
Evaluation of a topical treatment based on antimicrobial peptides against S.aureus MRSA in a three-dimensional in-vitro human skin model. PI: Juan Carlos Cruz. Call 777 Colciencias. Code No 120477757832.

 

financing
Evaluation of the use of antimicrobial peptides to combat infections caused by S. aureus MRSA in an in-vitro cutaneous wound model. PI: Juan Carlos Briceño. Participation as co-investigator. 2017, Internal Call for Support in Strengthening FCI Groups. Funded.

julian serna

Julián Serna, MSc.

monica cuellar

Mónica Cuellar, MSc.

BioTissue (Tissuetech Inc.)

alejandra suarez

Alejandra Suarez, MSc.

PhD student at Duke University

laura ellis

Laura Ellis, MSc.

daniela cespedes

Daniela Céspedes, MSc.

Boston Scientific

paula guerrero

Paula Guerrero, MSc.

Medtronic

sabina nieto

Sabina Nieto

Undergraduate Student

santiago sanchez

Santiago Sánchez

Master's Student in Chemical Engineering

juliana casas

Juliana Casas

isabella munoz

Isabella Muñoz

maria ximena forero

Maria Ximena Forero